Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction

Myasthenia gravis (MG) is a rare autoantibody-mediated disease affecting the neuromuscular junction. We performed a genome-wide association study of 5708 MG cases and 432,028 controls of European ancestry and a replication study in 3989 cases and 226,643 controls provided by 23andMe Inc. We identifi...

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Main Authors:	Braun, A, Shekhar, S, Levey, DF, Straub, P, Kraft, J, Panagiotaropoulou, GM, Heilbron, K, Awasthi, S, Meleka Hanna, R, Hoffmann, S, Stein, M, Lehnerer, S, Mergenthaler, P, Elnahas, AG, Topaloudi, A, Koromina, M, Palviainen, T, Asbjornsdottir, B, Stefansson, H, Skuladóttir, AT, Jónsdóttir, I, Stefansson, K, Reis, K, Esko, T
Format:	Journal article
Language:	English
Published:	Nature Research 2024

Genome-wide meta-analysis of myasthenia gravis uncovers new loci and provides insights into polygenic prediction

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