PX- and FYVE-mediated interactions with membranes: simulation studies.

Molecular dynamics simulations have been used to explore the interactions of two PI(3)P-binding domains with their PI ligands and with a phospholipid bilayer. Three simulations each of the EEA1-FYVE domain and the p40(phox)-PX domain have been compared: with the protein in an apo state, with a bound...

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Bibliographic Details
Main Authors: Psachoulia, E, Sansom, MS
Format: Journal article
Language:English
Published: 2009