Alterations in receptor binding properties of recent human influenza H3N2 viruses are associated with reduced natural killer cell lysis of infected cells.

Alterations in receptor binding properties of recent human influenza H3N2 viruses are associated with reduced natural killer cell lysis of infected cells.

Natural killer (NK) cell recognition of influenza virus-infected cells involves hemagglutinin (HA) binding to sialic acid (SA) on activating NK receptors. SA also acts as a receptor for the binding of influenza virus to its target host cells. The SA binding properties of H3N2 influenza viruses have...

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Bibliographic Details
Main Authors: Owen, R, Yamada, E, Thompson, C, Phillipson, L, Taylor, E, Zambon, M, Osborn, H, Barclay, W, Borrow, P
Format: Journal article
Language:English
Published: 2007

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