Real-time dynamic modelling for the design of a cluster-randomized phase 3 Ebola vaccine trial in Sierra Leone

<p>Background</p> <p>Declining incidence and spatial heterogeneity complicated the design of phase 3 Ebola vaccine trials during the tail of the 2013–16 Ebola virus disease (EVD) epidemic in West Africa. Mathematical models can provide forecasts of expected incidence through time a...

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Bibliographic Details
Main Authors: Camacho, A, Eggo, R, Goeyvaerts, N, Vandebosch, A, Mogg, R, Funk, S, Kucharski, A, Watson, C, Vangeneugden, T, Edmunds, W
Format: Journal article
Language:English
Published: Elsevier 2016