Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data

To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. Mendelian randomisation meta-analysis of individual participant data from 47 epidemiological studies in 15 countries. 194418 participants, including 46557 patients...

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Bibliographic Details
Main Authors: Wensley, F, Gao, P, Burgess, S, Kaptoge, S, Di Angelantonio, E, Shah, T, Engert, J, Clarke, R, Davey-Smith, G, Nordestgaard, BG, Saleheen, D, Samani, N, Sandhu, M, Anand, S, Pepys, M, Smeeth, L, Whittaker, J, Casas, J, Thompson, S, Hingorani, A, Danesh, J, Eiriksdottir, G, Harris, T, Launer, L, Gudnason, V
Format: Journal article
Published: 2011