Pharmacokinetics of high-dose oseltamivir in healthy volunteers.

The effects of loading doses and probenecid coadministration on oseltamivir pharmacokinetics at four increasing dose levels in groups of eight healthy adult Thai volunteers (125 individual series) were evaluated. Doses of up to 675 mg were well-tolerated. The pharmacokinetics were dose linear. Oselt...

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Bibliographic Details
Main Authors: Wattanagoon, Y, Stepniewska, K, Lindegårdh, N, Pukrittayakamee, S, Silachamroon, U, Piyaphanee, W, Singtoroj, T, Hanpithakpong, W, Davies, G, Tarning, J, Pongtavornpinyo, W, Fukuda, C, Singhasivanon, P, Day, N, White, N
Format: Journal article
Language:English
Published: 2009