Functional characterisation of a novel heterozygous mutation in the transcriptional activation domain of the human FOXN1 gene

<p>The competence of the human body to fight infections relies on lymphocytes, which differentiate in the thymus, a primary organ of the immune system. There, thymic epithelial cells (TECs) have a unique role to instruct developing T lymphocytes to discriminate self-proteins from foreign patho...

Full description

Bibliographic Details
Main Author: Rota, I
Other Authors: Holländer, G
Format: Thesis
Language:English
Published: 2019
Subjects: