Copper catalyzed asymmetric synthesis of chiral allylic esters.
The complex derived from Taniaphos ligand 4 and CuBr*Me2S catalyzes the asymmetric addition of Grignard reagents to 3-bromopropenyl esters 1 to provide allylic esters 2 in high yields and high chemio-, regio-, and enantioselectivities. The work demonstrates that allylic asymmetric alkylation (AAA) c...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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