Alteration of gene expression in human cumulus cells as a potential indicator of oocyte aneuploidy.

BACKGROUND: Human female meiosis is particularly error prone, leading to the generation of aneuploidy, a problem which increases dramatically with advancing age. Despite being of great clinical importance, the genesis of oocyte aneuploidy remains poorly understood. Cumulus cells (CCs) surround oocy...

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Bibliographic Details
Main Authors: Fragouli, E, Wells, D, Iager, A, Kayisli, U, Patrizio, P
Format: Journal article
Language:English
Published: 2012