Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial.

Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial.

BACKGROUND: Lithium has neuroprotective effects in cell and animal models of amyotrophic lateral sclerosis (ALS), and a small pilot study in patients with ALS showed a significant effect of lithium on survival. We aimed to assess whether lithium improves survival in patients with ALS. METHODS: The l...

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Príomhchruthaitheoirí: Morrison, K, Dhariwal, S, Hornabrook, R, Savage, L, Burn, D, Khoo, T, Kelly, J, Murphy, C, Al-Chalabi, A, Dougherty, A, Leigh, P, Wijesekera, L, Thornhill, M, Ellis, C, O'Hanlon, K, Panicker, J, Pate, L, Ray, P, Wyatt, L, Young, C, Copeland, L, Ealing, J, Hamdalla, H, Leroi, I
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2013

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