THE ASYMMETRIC-SYNTHESIS OF BETA-LACTAMS - STEREOCONTROLLED ASYMMETRIC TANDEM MICHAEL ADDITIONS AND SUBSEQUENT ALKYLATIONS OF E-[(ETA-5-C5H5)FE(CO)(PPH3)COCH=CHME] - X-RAY CRYSTAL-STRUCTURE OF (RS)-E-[(ETA-5-C5H5)FE(CO)(PPH3)COCH - CHME]
Michael addition of methyllithium to the E-crotonyl complex (RS)-[η5-C5H5)Fe(CO)-(PPh3 )COCHCHMe] followed by trapping of the resultant enolate with methyl iodide gives (RS)-[(η5-C5H5)Fe(CO)(PPh3 )COCH(Me)CHMe2] (d.e. > 100:1), also generated by treatment of (RS)-[(η5-C5H5)Fe(CO)(PPh3 )COCH2C...
Autors principals: | , , , , , |
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Format: | Journal article |
Idioma: | English |
Publicat: |
1986
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