Genomic inflation factors under polygenic inheritance.

Genomic inflation factors under polygenic inheritance.

Hiển thị phiên bản (1) khác

Population structure, including population stratification and cryptic relatedness, can cause spurious associations in genome-wide association studies (GWAS). Usually, the scaled median or mean test statistic for association calculated from multiple single-nucleotide-polymorphisms across the genome i...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Yang, J, Weedon, M, Purcell, S, Lettre, G, Estrada, K, Willer, C, Smith, A, Ingelsson, E, O'Connell, JR, Mangino, M, Mägi, R, Madden, P, Heath, A, Nyholt, DR, Martin, N, Montgomery, G, Frayling, T, Hirschhorn, J, McCarthy, M, Goddard, M, Visscher, P
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	2011

Những quyển sách tương tự

Genomic inflation factors under polygenic inheritance
Bằng: Yang, J, et al.
Được phát hành: (2011)

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
Bằng: Yang, J, et al.
Được phát hành: (2012)

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis.
Bằng: Lee, S, et al.
Được phát hành: (2013)

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits.
Bằng: Yang, J, et al.
Được phát hành: (2012)

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
Bằng: Yang, J, et al.
Được phát hành: (2012)

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants
Bằng: Crouch, DJM, et al.
Được phát hành: (2020)

Common variants show predicted polygenic effects on height in the tails of the distribution, except in extremely short individuals.
Bằng: Yingleong Chan, et al.
Được phát hành: (2011-12-01)

Improved polygenic prediction by Bayesian multiple regression on summary statistics
Bằng: Luke R. Lloyd-Jones, et al.
Được phát hành: (2019-11-01)

Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration in a Spontaneous Polygenic Model of Inherited Retinal Dystrophy
Bằng: T. J. Hollingsworth, et al.
Được phát hành: (2022-03-01)

Food prices and inflation in Tanzania
Bằng: Adam, C, et al.
Được phát hành: (2017)

Genetic Analysis of Major Gene and Polygene Inheritance of Chlorophyll Content in Chieh-qua Pulp
Bằng: Yin GAO, et al.
Được phát hành: (2024-09-01)

Heritable polygenic editing: the next frontier in genomic medicine?
Bằng: Visscher, PM, et al.
Được phát hành: (2025)

Genetic Analysis of Flowering Time in Pansies Using Mixed Major Gene Plus Polygene Inheritance Model
Bằng: Jiayi Liu, et al.
Được phát hành: (2024-12-01)

Theoretical and empirical quantification of the accuracy of polygenic scores in ancestry divergent populations
Bằng: Ying Wang, et al.
Được phát hành: (2020-07-01)

Interrogating type 2 diabetes genome-wide association data using a biological pathway-based approach.
Bằng: Perry, JR, et al.
Được phát hành: (2009)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
Bằng: Clara Albiñana, et al.
Được phát hành: (2023-08-01)

Polygenic determinants in extremes of high-density lipoprotein cholesterol
Bằng: Jacqueline S. Dron, et al.
Được phát hành: (2017-11-01)

Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
Bằng: Emil Uffelmann, et al.
Được phát hành: (2023-03-01)

An ensemble penalized regression method for multi-ancestry polygenic risk prediction
Bằng: Jingning Zhang, et al.
Được phát hành: (2024-04-01)

Genome-wide association analysis of treatment resistant schizophrenia for variant discovery and polygenic assessment
Bằng: Hasan Çağın Lenk, et al.
Được phát hành: (2024-09-01)

No evidence of association of ENPP1 variants with type 2 diabetes or obesity in a study of 8,089 U.K. Caucasians.
Bằng: Weedon, M, et al.
Được phát hành: (2006)

Polygenic diseases
Bằng: Sergey Dolomatov, et al.
Được phát hành: (2025-01-01)

Variation and impact of polygenic hematologic traits in monogenic sickle cell disease
Bằng: Thomas Pincez, et al.
Được phát hành: (2022-10-01)

Reply to: Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates
Bằng: Rita Guerreiro, et al.
Được phát hành: (2023-03-01)

Variability of polygenic prediction for body mass index in Africa
Bằng: Tinashe Chikowore, et al.
Được phát hành: (2024-05-01)

Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood
Bằng: Ragna Bugge Askeland, et al.
Được phát hành: (2023-06-01)

Common variants at 30 loci contribute to polygenic dyslipidemia.
Bằng: Kathiresan, S, et al.
Được phát hành: (2009)

A simple and fast two-locus quality control test to detect false positives due to batch effects in genome-wide association studies.
Bằng: Lee, S, et al.
Được phát hành: (2010)

Assessment of polygenic risk of hypertension
Bằng: A. S. Limonova, et al.
Được phát hành: (2023-01-01)

A polygenic biomarker to identify patients with severe hypercholesterolemia of polygenic origin
Bằng: Luis G. Leal, et al.
Được phát hành: (2020-06-01)

P270: Characterizing clinical actionability in the context of polygenic risk assessment*
Bằng: Bradford Powell, et al.
Được phát hành: (2023-01-01)

Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries
Bằng: Zheng, Z, et al.
Được phát hành: (2024)

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification
Bằng: Kristi Läll, et al.
Được phát hành: (2019-06-01)

Polygenic risk score phenome-wide association study reveals an association between endometriosis and testosterone
Bằng: Isabelle M. McGrath, et al.
Được phát hành: (2023-12-01)

Functional variation in VEGF is not associated with type 2 diabetes in a United Kingdom Caucasian population.
Bằng: Freathy, R, et al.
Được phát hành: (2006)

A large-scale association analysis of common variation of the HNF1alpha gene with type 2 diabetes in the U.K. Caucasian population.
Bằng: Weedon, M, et al.
Được phát hành: (2005)

Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Bằng: Oleksandr Frei, et al.
Được phát hành: (2019-06-01)

Evaluation of common variants in the six known maturity-onset diabetes of the young (MODY) genes for association with type 2 diabetes.
Bằng: Winckler, W, et al.
Được phát hành: (2007)

THE GROUNDS OF INHERITANCE IN RUSSIAN INHERITANCE LAW
Bằng: I. Melnikova, et al.
Được phát hành: (2021-09-01)

Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15.
Bằng: Zondervan, K, et al.
Được phát hành: (2007)