Genome-wide study identifies association between HLA-B∗55:01 and self-reported penicillin allergy

Hypersensitivity reactions to drugs are often unpredictable and can be life threatening, underscoring a need for understanding their underlying mechanisms and risk factors. The extent to which germline genetic variation influences the risk of commonly reported drug allergies such as penicillin aller...

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Príomhchruthaitheoirí: Krebs, K, Bovijn, J, Zheng, N, Lepamets, M, Censin, JC, Jürgenson, T, Särg, D, Abner, E, Laisk, T, Luo, Y, Skotte, L, Geller, F, Feenstra, B, Wang, W, Auton, A, 23andMe Research Team, Raychaudhuri, S, Esko, T, Metspalu, A, Laur, S, Roden, DM, Wei, W-Q, Holmes, MV, Lindgren, CM, Phillips, EJ, Mägi, R, Milani, L, Fadista, J
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: Elsevier 2020