Mapping networks of alpha-Synuclein proteostasis in cellular models of Parkinson's disease pathology
Parkinson’s disease (PD) is the second most common neurodegenerative disorder for which there is no disease-modifying therapy. Pathologically, the neuronal loss correlates with abnormal accumulation, aggregation and toxic gain of function of the small pre-synaptic protein alpha-Synuclein (aSyn). Whe...
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Format: | Thesis |
Language: | English |
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2020
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