A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19

SARS-CoV-2 remains a global threat to human health particularly as escape mutants emerge. There is an unmet need for effective treatments against COVID-19 for which neutralizing single domain antibodies (nanobodies) have significant potential. Their small size and stability mean that nanobodies are...

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Bibliographic Details
Main Authors: Huo, J, Mikolajek, H, Le Bas, A, Clark, JJ, Sharma, P, Kipar, A, Dormon, J, Norman, C, Weckener, M, Clare, DK, Harrison, PJ, Tree, JA, Buttigieg, KR, Salguero, FJ, Watson, R, Knott, D, Carnell, O, Ngabo, D, Elmore, MJ, Fotheringham, S, Harding, A, Moynié, L, Ward, PN, Dumoux, M, Prince, T, Hall, Y, Hiscox, JA, Owen, A, James, W, Carroll, MW, Stewart, JP, Naismith, JH, Owens, RJ
Format: Journal article
Language:English
Published: Springer Nature 2021

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