Putting proteomics on target: activity-based profiling of ubiquitin and ubiquitin-like processing enzymes.
Modification of proteins with ubiquitin (Ub) and Ub-like modifiers (Ubls) plays a fundamental role in cell biology. As a consequence, proteomics-based efforts were developed to characterize proteins that are modified by Ub or Ubls. A more focused functional proteomics strategy relies on active-site...
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| Médium: | Journal article |
| Jazyk: | English |
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2006
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