Towards an engineered autologous cellular therapy for RAG2 deficiency

<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...

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Detalles Bibliográficos
Autor principal: Gardner, CL
Otros Autores: Acuto, O
Formato: Tesis
Lenguaje:English
Publicado: 2020
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