Towards an engineered autologous cellular therapy for RAG2 deficiency

<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...

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Détails bibliographiques
Auteur principal: Gardner, CL
Autres auteurs: Acuto, O
Format: Thèse
Langue:English
Publié: 2020
Sujets: