Towards an engineered autologous cellular therapy for RAG2 deficiency

<p>Severe combined immune deficiency (SCID) caused by RAG deficiency is a genetically-determined immune deficiency characterized by the virtual absence of adaptive immune cells. Unless treated with a hematopoietic stem cell transplantation (HSCT), RAG deficient patients succumb to severe infec...

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Detalhes bibliográficos
Autor principal: Gardner, CL
Outros Autores: Acuto, O
Formato: Thesis
Idioma:English
Publicado em: 2020
Assuntos: