Human fetal B-lymphopoiesis and acute lymphoblastic leukaemia: the impact of trisomy 21
<p><strong>Background:</strong> Children with Down Syndrome (DS), caused by an extra copy of chromosome 21 (trisomy 21, T21) are at increased risk of developing acute myeloid leukaemia (ML-DS) and B lineage acute lymphoblastic leukaemia (ALL). This points to specific effects of T21...
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2019
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