Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection.
Mutations within cytotoxic T lymphocyte (CTL) epitopes impair T cell recognition, but escape mutations arising in flanking regions that alter antigen processing have not been defined in natural human infections. In human histocompatibility leukocyte antigen (HLA)-B57+ HIV-infected persons, immune se...
Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2004
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