CYP2B6*6 genotype specific differences in artemether‐lumefantrine disposition in healthy volunteers

<p>Cytochrome P450 2B6 (CYP2B6) is involved in the metabolism of the antimalarial drugs artemether and lumefantrine. Here we investigated the effect of&nbsp;<em>CYP2B6</em>*6 on the plasma pharmacokinetics of artemether, lumefantrine, and their metabolites in healthy volunteers...

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Bibliographic Details
Main Authors: Abdullahi, ST, Soyinka, JO, Olagunju, A, Bolarinwa, RA, Olarewaju, OJ, Bakare-Odunola, MT, Winterberg, M, Tarning, J, Owen, A, Khoo, S
Format: Journal article
Language:English
Published: Wiley 2019