A coordinated synthesis and conjugation strategy for the preparation of homogeneous glycoconjugate vaccine candidates.

A sweet solution: A strategy for the synthesis of well-defined carbohydrate-based vaccines is presented. The approach couples complex oligosaccharide synthesis to site-specific conjugation methodology to provide pure glycoprotein vaccine candidates (see scheme). Copyright © 2011 WILEY-VCH Verlag Gmb...

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Bibliographic Details
Main Authors: Grayson, E, Bernardes, G, Chalker, J, Boutureira, O, Koeppe, JR, Davis, B
Format: Journal article
Language:English
Published: 2011