CD8 epitope escape and reversion in acute HCV infection.
In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8+ cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70-80% of individuals develop persistent infection. Although viral escape from CD8 responses has been il...
Autors principals: | , , , , , , , , , , , , , , , |
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Format: | Journal article |
Idioma: | English |
Publicat: |
2004
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