CD8 epitope escape and reversion in acute HCV infection.
In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8+ cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70-80% of individuals develop persistent infection. Although viral escape from CD8 responses has been il...
Main Authors: | Timm, J, Lauer, G, Kavanagh, D, Sheridan, I, Kim, A, Lucas, M, Pillay, T, Ouchi, K, Reyor, L, Schulze zur Wiesch, J, Gandhi, RT, Chung, RT, Bhardwaj, N, Klenerman, P, Walker, B, Allen, T |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2004
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