CD8 epitope escape and reversion in acute HCV infection.

CD8 epitope escape and reversion in acute HCV infection.

In the setting of acute hepatitis C virus (HCV) infection, robust HCV-specific CD8+ cytotoxic T lymphocyte (CTL) responses are associated with initial control of viremia. Despite these responses, 70-80% of individuals develop persistent infection. Although viral escape from CD8 responses has been il...

Podrobná bibliografie
Hlavní autoři:	Timm, J, Lauer, G, Kavanagh, D, Sheridan, I, Kim, A, Lucas, M, Pillay, T, Ouchi, K, Reyor, L, Schulze zur Wiesch, J, Gandhi, RT, Chung, RT, Bhardwaj, N, Klenerman, P, Walker, B, Allen, T
Médium:	Journal article
Jazyk:	English
Vydáno:	2004

Podobné jednotky

CTL epitope escape and reversion in acute HCV infection.
Autor: Timm, J, a další
Vydáno: (2004)

High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome
Autor: Kasprowicz, V, a další
Vydáno: (2011)

High level of PD-1 expression on hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells during acute HCV infection, irrespective of clinical outcome.
Autor: Kasprowicz, V, a další
Vydáno: (2008)

Full-breadth analysis of CD8+ T-cell responses in acute hepatitis C virus infection and early therapy.
Autor: Lauer, G, a další
Vydáno: (2005)

T-cell responses during early therapy for HCV infection.
Autor: Lauer, G, a další
Vydáno: (2003)

Comprehensive analysis of the HCV-specific CD8+T cell response in individuals with chronic or resolved HCV infection.
Autor: Lauer, G, a další
Vydáno: (2001)

High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8(+) and CD4(+) T Cells during Acute HCV Infection, Irrespective of Clinical Outcome (vol 82, pg 3154, 2008)
Autor: Kasprowicz, V, a další
Vydáno: (2011)

Comprehensive longitudinal analysis of cellular immune responses and viral evolution in a person with acute HCV infection requiring antiviral treatment.
Autor: Lauer, G, a další
Vydáno: (2002)

Do antiviral CD8+ T cells select hepatitis C virus escape mutants? Analysis in diverse epitopes targeted by human intrahepatic CD8+ T lymphocytes.
Autor: Komatsu, H, a další
Vydáno: (2006)

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution
Autor: Kasprowicz, V, a další
Vydáno: (2011)

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.
Autor: Kasprowicz, V, a další
Vydáno: (2010)

The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1.
Autor: Kim, A, a další
Vydáno: (2005)

Comprehensive Review of Human Plasmodium falciparum-Specific CD8+ T Cell Epitopes
Autor: Janna Heide, a další
Vydáno: (2019-03-01)

Human hepatitis D virus-specific T cell epitopesKey points
Autor: Matin Kohsar, a další
Vydáno: (2021-08-01)

OA06-03. Dynamics of CTL epitope escape and reversion in an African subtype C cohort
Autor: Allen S, a další
Vydáno: (2009-10-01)

Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution (vol 84, pg 1656, 2010)
Autor: Kasprowicz, V, a další
Vydáno: (2011)

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.
Autor: Palmer, D, a další
Vydáno: (2013)

Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes.
Autor: Palmer, D, a další
Vydáno: (2013)

MULTIPLE NOVEL PEPTIDE EPITOPES IN HCV GENOTYPE-3A IDENTIFIED USING TWO PARALLEL APPROACHES
Autor: Boehmer, A, a další
Vydáno: (2011)

Longitudinal mapping of protective CD4+ T cell responses against HCV: analysis of fluctuating dominant and subdominant HLA-DR11 restricted epitopes.
Autor: Harcourt, G, a další
Vydáno: (2004)

A pan-genotype HCV T cell vaccine, in a simian adenovirus vector, to target T cell epitopes conserved across multiple HCV genotypes
Autor: Donnison, T, a další
Vydáno: (2018)

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection.
Autor: Lauer, G, a další
Vydáno: (2004)

Detection of EXP1-Specific CD4+ T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria
Autor: Janna Heide, a další
Vydáno: (2020-01-01)

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate.
Autor: Zhen-yong Keck, a další
Vydáno: (2012-01-01)

CYTOTOXIC T-LYMPHOCYTE RECOGNITION OF HIV - EPITOPE SELECTION AND ESCAPE
Autor: Mcmichael, A, a další
Vydáno: (1993)

CD8AA T CELLS: A NOVEL LINEAGE ENRICHED IN THE LIVER IN CHRONIC HCV
Autor: Walker, L, a další
Vydáno: (2010)

An elite controller of picornavirus infection targets an epitope that is resistant to immune escape.
Autor: Michael P Bell, a další
Vydáno: (2014-01-01)

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
Autor: Dazert, E, a další
Vydáno: (2009)

Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities.
Autor: Lauer, G, a další
Vydáno: (2002)

Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.
Autor: Liu, M, a další
Vydáno: (2013)

VIRAL FITNESS COST AND T CELL CROSS-RECOGNITION LIMIT VIRAL ESCAPE WITHIN A PROTECTIVE HLA-B27 RESTRICTED HEPATITIS C VIRUS SPECIFIC CD8+T CELL EPITOPE
Autor: Neumann-Haefelin, C, a další
Vydáno: (2008)

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection.
Autor: Crawford, H, a další
Vydáno: (2007)

Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition
Autor: Nils H. Wildner, a další
Vydáno: (2022-06-01)

Reversal of T Cell Exhaustion in Chronic HCV Infection
Autor: Sylwia Osuch, a další
Vydáno: (2020-07-01)

Analysis of HCV in South East Asia
Autor: Barnes, E, a další
Vydáno: (2007)

Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design
Autor: Vanessa M. Cowton, a další
Vydáno: (2021-01-01)

Genotypic resistance testing of HCV – is there a clinical need?
Autor: Walker, Andreas, a další
Vydáno: (2016-08-01)

Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles
Autor: Andreas Walker, a další
Vydáno: (2022-11-01)

CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
Autor: Sylvain Cardinaud, a další
Vydáno: (2011-05-01)

HCV-indeterminate blood donors or occult HCV infection? Reply
Autor: Semmo, N, a další
Vydáno: (2005)