Membranes as messengers in T cell adhesion signaling.
Talin and RapL are components of molecular pathways that regulate the avidity of the integrin lymphocyte function-associated antigen 1 (LFA-1) for its ligand, intercellular adhesion molecule 1. In this review, we discuss recent advances in our understanding of LFA-1 affinity regulation and signaling...
Autori principali: | Dustin, M, Bivona, T, Philips, MR |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2004
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