CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia.

T-cell acute lymphoblastic leukaemia (T-ALL) is a blood malignancy afflicting mainly children and adolescents. T-ALL patients present at diagnosis with increased white cell counts and hepatosplenomegaly, and are at an increased risk of central nervous system (CNS) relapse. For that reason, T-ALL pat...

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Bibliographic Details
Main Authors: Buonamici, S, Trimarchi, T, Ruocco, MG, Reavie, L, Cathelin, S, Mar, BG, Klinakis, A, Lukyanov, Y, Tseng, J, Sen, F, Gehrie, E, Li, M, Newcomb, E, Zavadil, J, Meruelo, D, Lipp, M, Ibrahim, S, Efstratiadis, A, Zagzag, D, Bromberg, J, Dustin, M, Aifantis, I
Format: Journal article
Language:English
Published: 2009