MacroD1 is a promiscuous ADP-ribosyl hydrolase localized to mitochondria

MacroD1 is a promiscuous ADP-ribosyl hydrolase localized to mitochondria

MacroD1 is a macrodomain containing protein that has mono-ADP-ribose hydrolase enzymatic activity toward several ADP-ribose adducts. Dysregulation of MacroD1 expression has been shown to be associated with the pathogenesis of several forms of cancer. To date, the physiological functions and sub-cell...

Полное описание

Библиографические подробности
Главные авторы:	Agnew, T, Munnur, D, Crawford, K, Palazzo, L, Mikoč, A, Ahel, I
Формат:	Journal article
Язык:	English
Опубликовано:	Frontiers Media 2018

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