Increased cardiac Pi/PCr in the diabetic heart observed using phosphorus magnetic resonance spectroscopy at 7T

Phosphorus magnetic resonance spectroscopy (31P-MRS) has previously demonstrated decreased energy reserves in the form of phosphocreatine to adenosine-tri-phosphate ratio (PCr/ATP) in the hearts of patients with type 2 diabetes (T2DM). Recent 31P-MRS techniques using 7T systems, e.g. long mixing tim...

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Bibliographic Details
Main Authors: Valkovič, L, Apps, A, Ellis, J, Neubauer, S, Tyler, DJ, Schmid, AI, Rider, OJ, Rodgers, CT
Format: Journal article
Language:English
Published: Public Library of Science 2022