Decreased 5-HT-mediated prolactin release in major depression.

The prolactin response to intravenous clomipramine, a 5-HT uptake inhibitor, was significantly attenuated in 12 patients with major depression. In contrast, in a further 12 depressed patients, the PRL responses to thyrotropin-releasing hormone, which acts directly on the pituitary to release PRL, we...

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Bibliographic Details
Main Authors: Anderson, I, Ware, C, da Roza Davis, J, Cowen, P
Format: Journal article
Language:English
Published: 1992