Development of a sensitive, scalable method for spatial, cell-type-resolved proteomics of the human brain

While nearly comprehensive proteome coverage can be achieved from bulk tissue or cultured cells, the data usually lacks spatial resolution. As a result, tissue based proteomics averages protein abundance across multiple cell types and/or localizations. With proteomics platforms lacking sensitivity a...

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Detalhes bibliográficos
Main Authors: Davis, S, Scott, C, Ansorge, O, Fischer, R
Formato: Journal article
Idioma:English
Publicado em: American Chemical Society 2019