Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons.

Striatal dopamine plays key roles in our normal and pathological goal-directed actions. To understand dopamine function, much attention has focused on how midbrain dopamine neurons modulate their firing patterns. However, we identify a presynaptic mechanism that triggers dopamine release directly, b...

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Bibliographic Details
Main Authors: Threlfell, S, Lalic, T, Platt, N, Jennings, K, Deisseroth, K, Cragg, S
Format: Journal article
Language:English
Published: 2012