Renal transplant immunosuppression impairs natural killer cell function in vitro and in vivo.

BACKGROUND: Despite an increasing awareness of the importance of innate immunity, the roles of natural killer (NK) cells in transplant rejection and antiviral and cancer immunity during immunosuppression have not been clearly defined. METHODS: To address this issue we have developed a quantitative a...

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Bibliographic Details
Main Authors: Morteau, O, Blundell, S, Chakera, A, Bennett, S, Christou, C, Mason, P, Cornall, R, O'Callaghan, C
Format: Journal article
Language:English
Published: Public Library of Science 2010