Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing

Necrotising fasciitis (NF) is a rare manifestation of invasive Streptococcus pyogenes (GAS) infection associated with a substantial risk of death or disability. Hypothesising that host genetic factors might contribute, we sought to identify rare deleterious variants contributing to NF susceptibility...

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Main Authors:	Parks, T, Elliott, K, Lamagni, T, Malinauskas, T, Murphy, M, Petherbridge, L, Guy, R, Auckland, K, Mentzer, A, Marsden, D, Strakova, L, Chapman, S, Hill, A, Sriskandan, S, Knight, J
Format:	Conference item
Published:	European Society of Clinical Microbiology and Infectious Disease 2018

Rare deleterious variants in genes involved in tissue structure and epithelial integrity are found in patients with group A streptococcal necrotising fasciitis by whole-exome sequencing

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