Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states.

Polymodal activation of the TREK-2 K2P channel produces structurally distinct open states.

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The TREK subfamily of two-pore domain (K2P) K+ channels exhibit polymodal gating by a wide range of physical and chemical stimuli. Crystal structures now exist for these channels in two main states referred to as the “up” and “down” conformations. However, recent studies have resulted in contradicto...

書目詳細資料
Main Authors:	McClenaghan, C, Schewe, M, Aryal, P, Carpenter, E, Baukrowitz, T, Tucker, S
格式:	Journal article
語言:	English
出版:	Rockefeller University Press 2016

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