Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol

Purpose To prospectively validate two risk scores to predict mortality (4C Mortality) and in-hospital deterioration (4C Deterioration) among adults hospitalised with COVID-19. Methods Prospective observational cohort study of adults (age ≥18 years) with confirmed or highly suspected COVID-19 recrui...

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Main Authors: Knight, SR, Gupta, RK, Ho, A, Pius, R, Buchan, I, Carson, G, Drake, TM, Dunning, J, Fairfield, CJ, Gamble, C, Green, CA, Halpin, S, Hardwick, HE, Holden, KA, Horby, PW, Jackson, C, Mclean, KA, Merson, L, Nguyen-Van-Tam, JS, Norman, L, Olliaro, PL, Pritchard, MG, Russell, CD, Shaw, CA, Sheikh, A, Solomon, T, Sudlow, C, Swann, OV, Turtle, LCW, Openshaw, PJM, Baillie, JK, Docherty, A, Semple, MG, Noursadeghi, M, Harrison, EM
Other Authors: ISARIC Coronavirus Clinical Characterisation Consortium (ISARIC4C) Investigators
Format: Journal article
Language:English
Published: BMJ Publishing Group 2021