Choroideremia: molecular mechanisms and development of AAV gene therapy
<p><strong>Introduction:</strong> Choroideremia is an X-linked inherited retinal degeneration that causes blindness in afflicted males by middle age. The causative gene, CHM, plays a key role in intracellular trafficking pathways, and its disruption impairs cell homeostasis.</p&...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Taylor and Francis
2018
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