Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells.

p21-activated kinases (PAKs) are serine/threonine protein kinases that serve as important mediators of Rac and Cdc42 GTPase function as well as pathways required for Ras-driven tumorigenesis. PAK1 has been implicated in signaling by growth factor receptors and morphogenetic processes that control ce...

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Bibliographic Details
Main Authors:	Ong, C, Jubb, A, Haverty, P, Zhou, W, Tran, V, Truong, T, Turley, H, O'Brien, T, Vucic, D, Harris, A, Belvin, M, Friedman, L, Blackwood, E, Koeppen, H, Hoeflich, K
Format:	Journal article
Language:	English
Published:	2011

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells.

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