Rapamycin in ischemic stroke: Old drug, new tricks?

Rapamycin in ischemic stroke: Old drug, new tricks?

The significant morbidity that accompanies stroke makes it one of the world's most devastating neurological disorders. Currently, proven effective therapies have been limited to thrombolysis and thrombectomy. The window for the administration of these therapies is narrow, hampered by the necess...

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Manylion Llyfryddiaeth
Prif Awduron:	Hadley, G, Beard, D, Couch, Y, Neuhaus, A, Adriaanse, B, De Luca, G, Sutherland, B, Buchan, A
Fformat:	Journal article
Cyhoeddwyd:	SAGE Publications 2018

Eitemau Tebyg

Importance of preclinical research in the development of neuroprotective strategies for ischemic stroke.
gan: Neuhaus, A, et al.
Cyhoeddwyd: (2014)

The role of the endoplasmic reticulum stress response following cerebral ischemia
gan: Hadley, G, et al.
Cyhoeddwyd: (2017)

Neuroprotection in stroke: the importance of collaboration and reproducibility.
gan: Neuhaus, A, et al.
Cyhoeddwyd: (2017)

The effect of rapamycin treatment on cerebral ischemia: A systematic review and meta-analysis of animal model studies
gan: Beard, D, et al.
Cyhoeddwyd: (2018)

Rapamycin induces an eNOS dependent increase in brain collateral perfusion after acute experimental stroke in rats
gan: Beard, DJ, et al.
Cyhoeddwyd: (2019)

The transient intraluminal filament middle cerebral artery occlusion model as a model of endovascular thrombectomy in stroke
gan: Sutherland, B, et al.
Cyhoeddwyd: (2015)

A systematic review and meta-analysis of randomized controlled trials of endovascular thrombectomy compared with best medical treatment for acute ischemic stroke
gan: Balami, J, et al.
Cyhoeddwyd: (2015)

Understanding and managing ischemic stroke.
gan: Barber, P, et al.
Cyhoeddwyd: (2001)

Teaching old drugs new tricks
gan: Alexandre Faille, et al.
Cyhoeddwyd: (2022-12-01)

Novel method to study pericyte contractility and responses to ischaemia in vitro using electrical impedance
gan: Neuhaus, A, et al.
Cyhoeddwyd: (2016)

Can we teach an old drug new tricks?
gan: Ch'ng, J, et al.
Cyhoeddwyd: (2012)

Can we teach an old drug new tricks?
gan: Ch'ng, J, et al.
Cyhoeddwyd: (2012)

Reply: Thrombolysis in acute ischaemic stroke.
gan: Balami, J, et al.
Cyhoeddwyd: (2014)

Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses
gan: Stacey L. P. Scroggs, et al.
Cyhoeddwyd: (2020-09-01)

The exact science of stroke thrombolysis and the quiet art of patient selection.
gan: Balami, J, et al.
Cyhoeddwyd: (2013)

Reply: Intravenous thrombolysis for ischaemic strokes: a call for reappraisal.
gan: Balami, J, et al.
Cyhoeddwyd: (2014)

Overcoming resistance to immunotherapy by teaching old drugs new tricks
gan: John M. Perry, et al.
Cyhoeddwyd: (2020-09-01)

Investigation of the novel mTOR inhibitor AZD2014 in neuronal ischemia
gan: Hadley, G, et al.
Cyhoeddwyd: (2019)

An Old Brain with New Tricks
gan: Kristen Rae Spicer, et al.
Cyhoeddwyd: (2010-09-01)

Etomoxir: an old dog with new tricks
gan: Reagan M. McGuffee, et al.
Cyhoeddwyd: (2024-09-01)

Graft-versus-host disease: teaching old drugs new tricks at less cost
gan: Shatha Farhan, et al.
Cyhoeddwyd: (2023-08-01)

Smoking cessation 2: Nicotine replacement therapy - new tricks with old drugs
gan: Aveyard, P, et al.
Cyhoeddwyd: (2009)

Use of repurposed drugs in COVID-19 pandemic: Old drugs without new tricks?
gan: Suraj Kapoor
Cyhoeddwyd: (2023-01-01)

Treatment of the patient with acute ischemic stroke
gan: Klein, G, et al.
Cyhoeddwyd: (1998)

Methadone - An Old Analgesic with New Tricks
gan: DE Moulin
Cyhoeddwyd: (2005-01-01)

Alum: an old dog with new tricks
gan: Yumei Wen, et al.
Cyhoeddwyd: (2016-01-01)

A new trick for an old lipid
gan: Hayley Sharpe
Cyhoeddwyd: (2016-11-01)

Teaching new dogs old tricks
gan: Robertson Miranda
Cyhoeddwyd: (2009-04-01)

Biochemistry of ischemic stroke.
gan: Barber, P, et al.
Cyhoeddwyd: (2003)

Teaching an old drug new tricks: Regulatory insights for the repurposing of hemin in cardiovascular disease
gan: Ashley L. Eadie, et al.
Cyhoeddwyd: (2024-08-01)

Old Drug, New Trick? Oral Milrinone for Heart Failure With Preserved Ejection Fraction
gan: Daniel N. Silverman, et al.
Cyhoeddwyd: (2020-07-01)

N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks)
gan: Gerry K. Schwalfenberg
Cyhoeddwyd: (2021-01-01)

Adenosine, lidocaine and Mg2+ update: teaching old drugs new tricks
gan: Geoffrey P. Dobson, et al.
Cyhoeddwyd: (2023-09-01)

Strategies for therapy in acute ischemic stroke.
gan: Buchan, A, et al.
Cyhoeddwyd: (2007)

The effects of fasting on acute ischemic infarcts in the rat
gan: Schneider, AM, et al.
Cyhoeddwyd: (2024)

Growth differentiation factor-11 causes neurotoxicity during ischemia in vitro
gan: Sutherland, BA, et al.
Cyhoeddwyd: (2020)

Novel macrocycles – and old ones doing new tricks
gan: Wei Jiang, et al.
Cyhoeddwyd: (2019-08-01)

Adenovirus: teaching an old dog new tricks.
gan: Seymour, L, et al.
Cyhoeddwyd: (2011)

Mass spectrometry: an old dog with new tricks
gan: Fran Lake
Cyhoeddwyd: (2021-03-01)

Guest Editorial: Old Dog. Same Trick
gan: David Jardine
Cyhoeddwyd: (2014-11-01)