Model complexes of cobalt-substituted matrix metalloproteinases: tools for inhibitor design.

The tetrahedral cobalt(II) complex [(Tp(Ph,Me))CoCl] (Tp(Ph,Me) = hydrotris(3,5-phenylmethylpyrazolyl)borate) was combined with several hydroxypyridinone, hydroxypyridinethione, pyrone, and thiopyrone ligands to form the corresponding [(Tp(Ph,Me))Co(L)] complexes. X-ray crystal structures of these c...

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Bibliographic Details
Main Authors: Jacobsen, F, Breece, R, Myers, W, Tierney, D, Cohen, S
Format: Journal article
Language:English
Published: 2006