Hyporesponsiveness of intestinal dendritic cells to TLR stimulation is limited to TLR4.

Dendritic cells (DCs) are crucial to intestinal immune regulation because of their roles in inducing protective immunity against pathogens while maintaining tolerance to commensal bacteria. Nonetheless, relatively little is known about intestinal DC responsiveness to innate immune stimuli via TLRs....

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Bibliographic Details
Main Authors: Cerovic, V, Jenkins, C, Barnes, A, Milling, S, Macpherson, G, Klavinskis, L
Format: Journal article
Language:English
Published: 2009