Multiple origins of the sickle mutation: evidence from beta S globin gene cluster polymorphisms.

Multiple origins of the sickle mutation: evidence from beta S globin gene cluster polymorphisms.

Restriction site polymorphisms of the beta globin gene cluster of 244 Jamaican beta S chromosomes have been studied. Various patterns of restriction site polymorphisms (haplotypes) both 5' and 3' to the beta gene have been found. These two groups of haplotypes were found to be non-randomiz...

書誌詳細
主要な著者:	Wainscoat, J, Bell, J, Thein, S, Higgs, D, Sarjeant, G, Peto, T, Weatherall, D
フォーマット:	Journal article
言語:	English
出版事項:	1983

類似資料

GEOGRAPHIC-DISTRIBUTION OF ALPHA-GLOBIN AND BETA-GLOBIN GENE-CLUSTER POLYMORPHISMS
著者:: Wainscoat, J, 等
出版事項: (1989)

The evolution of the alpha- and beta-globin gene clusters in human populations.
著者:: Hill, A, 等
出版事項: (1986)

A silent deletion in the beta-globin gene cluster.
著者:: Tate, V, 等
出版事項: (1986)

Analysis of the human alpha-globin gene cluster reveals a highly informative genetic locus.
著者:: Higgs, D, 等
出版事項: (1986)

Molecular rearrangements of the human alpha-globin gene cluster.
著者:: Higgs, D, 等
出版事項: (1985)

CHARACTERIZATION OF BETA-GLOBIN MESSENGER-RNA IN BETA-O THALASSEMIAS
著者:: Old, J, 等
出版事項: (1978)

Characterization of beta-globin mRNA in the beta0 thalassemias.
著者:: Old, J, 等
出版事項: (1978)

Beta-globin gene cluster haplotypes in Venezuelan sickle cell patients from the State of Aragua
著者:: Nancy Moreno, 等
出版事項: (2002-01-01)

Sickle cell anemia: clinical diversity and beta S-globin haplotypes
著者:: Sandra Regina Loggetto
出版事項: (2013-06-01)

Alpha globin genotypes in two North European populations.
著者:: Flint, J, 等
出版事項: (1986)

The evolution of the α- and β-globin gene clusters in human populations
著者:: Hill, A, 等
出版事項: (1986)

Globin genes in Micronesia: origins and affinities of Pacific Island peoples.
著者:: O'Shaughnessy, D, 等
出版事項: (1990)

Beta globin gene cluster haplotypes of the beta thalassemia mutations observed in the Denizli province of Turkey
著者:: Anzel Bahadır, 等
出版事項: (2009-09-01)

The interaction of alpha thalassaemia and sickle cell-beta zero thalassaemia.
著者:: Vyas, P, 等
出版事項: (1988)

Polynesian origins and affinities: globin gene variants in eastern Polynesia.
著者:: Hill, A, 等
出版事項: (1987)

Analysis of beta globin gene mutations in Diyarbakir
著者:: Tekeş Selahaddin, 等
出版事項: (2021-11-01)

Frequency of beta S globin gene haplotypes among sickle cell patients in Nigeria
著者:: Abosede Adabale, 等
出版事項: (2021-06-01)

Identification of mutations in a trans-acting factor with different effects on alpha and beta globin expression.
著者:: Viprakasit, V, 等
出版事項: (2000)

Identification of mutations in a trans-acting factor with different effects on alpha and beta globin expression.
著者:: Viprakasit, V, 等
出版事項: (2000)

Statistical methodology in the analysis of relationships between DNA polymorphisms and disease: putative association of Ha-ras-I hypervariable alleles and cancer.
著者:: Peto, T, 等
出版事項: (1988)

Intergenic transcription in the human beta-globin gene cluster.
著者:: Plant, K, 等
出版事項: (2001)

Analysis of the human alpha-globin gene cluster in transgenic mice.
著者:: Sharpe, J, 等
出版事項: (1993)

Independent recombination events between the duplicated human alpha globin genes; implications for their concerted evolution.
著者:: Higgs, D, 等
出版事項: (1984)

Detection of Rare Beta Globin Gene Mutations in Northwestern Iran
著者:: M Haghi, 等
出版事項: (2007-04-01)

Beta-globin gene cluster haplotypes in the Mapuche Indians of Argentina
著者:: Letícia Kaufman, 等
出版事項: (1998-12-01)

Beta-S globin haplotypes in patients with sickle cell anemia: one approach to understand the diversity in Brazil
著者:: Jéssika Viviani Okumura, 等
出版事項: (2013-01-01)

The beta-globin dominant control region.
著者:: Greaves, D, 等
出版事項: (1989)

Beta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis
著者:: Clark, B, 等
出版事項: (2016)

Hematologic features of beta-globin gene mutation type (?o) with homozygous beta thalassemia
著者:: Guluzar Ozbolat, 等
出版事項: (2018-07-01)

Frequency of Beta-globin gene mutations in beta-thalassemia patients from east of Mazandaran
著者:: Mohammad Bagher Hashemi Soteh, 等
出版事項: (2008-01-01)

Direct measurement of the male recombination fraction in the human beta-globin hot spot.
著者:: Schneider, J, 等
出版事項: (2002)

Determinação de haplótipos do gene beta S em pacientes com anemia falciforme Investigation of beta-globin gene cluster haplotypes in sickle cell anemia patients
著者:: Cynthia Hatsue Kitayama Cabral
出版事項: (2010-01-01)

SPECTRUM OF BETA GLOBIN GENE MUTATIONS IN EGYPTIAN CHILDREN WITH β- THALASSEMIA
著者:: MR El-Shanshory, 等
出版事項: (2014-08-01)

Dicer-dependent turnover of intergenic transcripts from the human beta-globin gene cluster.
著者:: Haussecker, D, 等
出版事項: (2005)

Beta-globin gene mutations in children with beta-thalassemia major from Şanlıurfa province, Turkey
著者:: Ali Ayçiçek, 等
出版事項: (2011-12-01)

Beta-globin gene mutations in children with beta-thalassemia major from Şanlıurfa province, Turkey
著者:: Ali Ayçiçek, 等
出版事項: (2011-12-01)

Phenotype/genotype relationships in sickle cell disease: a pilot twin study.
著者:: Weatherall, M, 等
出版事項: (2005)

Analysis of DNA Methylation at the Human Alpha Globin Cluster during Hematopoiesis
著者:: Ekwattanakit, S, 等
出版事項: (2008)

Alpha‐globin gene triplication and its effect in beta‐thalassemia carrier, sickle cell trait, and healthy individual
著者:: Mohammad Hamid, 等
出版事項: (2021-08-01)

Deletion of the alpha-globin gene cluster as a cause of acquired alpha-thalassemia in myelodysplastic syndrome.
著者:: Steensma, D, 等
出版事項: (2004)