Regulation of the Fanconi anemia DNA repair pathway by phosphorylation of FANCD2

Regulation of the Fanconi anemia DNA repair pathway by phosphorylation of FANCD2

<p>Living organisms have evolved multiple repair pathways that recognize and tackle different types of DNA damage. One such pathway is the Fanconi anemia DNA repair pathway which is able to repair DNA interstrand crosslinks (ICLs) – deleterious lesions arising by a covalent binding of the oppo...

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Bibliografiske detaljer
Hovedforfatter:	Kupculak, M
Andre forfattere:	Cohn, M
Format:	Thesis
Sprog:	English
Udgivet:	2020

Lignende værker

Phosphorylation of FANCD2 inhibits the FANCD2/FANCI complex and suppresses the Fanconi anemia pathway in the absence of DNA damage
af: Lopez-Martinez, D, et al.
Udgivet: (2019)

Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
af: David Lopez-Martinez, et al.
Udgivet: (2019-06-01)

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
af: Kupculak, M, et al.
Udgivet: (2023)

Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
af: Marian Kupculak, et al.
Udgivet: (2023-07-01)

Characterisation of novel phosphorylation sites on FANCD2 and their role in the Fanconi anaemia pathway
af: Lopez-Martinez, D
Udgivet: (2018)

DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination
af: Lixian Chang, et al.
Udgivet: (2021-07-01)

UHRF1 Is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi Anemia pathway
af: Liang, C, et al.
Udgivet: (2015)

A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair.
af: Matsushita, N, et al.
Udgivet: (2005)

UHRF1 Is a Sensor for DNA Interstrand Crosslinks and Recruits FANCD2 to Initiate the Fanconi Anemia Pathway
af: Chih-Chao Liang, et al.
Udgivet: (2015-03-01)

High-risk human papillomavirus oncogenes disrupt the Fanconi anemia DNA repair pathway by impairing localization and de-ubiquitination of FancD2.
af: Sujita Khanal, et al.
Udgivet: (2019-02-01)

Phosphorylation and dephosphorylation regulate the Fanconi anaemia DNA repair pathway
af: Yang, D
Udgivet: (2023)

Defective FANCI binding by a fanconi anemia-related FANCD2 mutant.
af: Koichi Sato, et al.
Udgivet: (2014-01-01)

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays
af: Winnie Tan, et al.
Udgivet: (2020-03-01)

FANCD2 Western blot as a diagnostic tool for Brazilian patients with Fanconi anemia
af: D.V. Pilonetto, et al.
Udgivet: (2009-03-01)

Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.
af: Nobuko Matsushita, et al.
Udgivet: (2011-01-01)

Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
af: Estefanía Burgos-Morón, et al.
Udgivet: (2016-07-01)

Uncovering roles of proteins in the Fanconi Anemia DNA repair pathway
af: Xu, H
Udgivet: (2024)

DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response
af: Fengshan Liang, et al.
Udgivet: (2019-06-01)

Deubiquitination of FANCD2 is required for DNA crosslink repair.
af: Oestergaard, V, et al.
Udgivet: (2007)

Deficiency of UBE2T, the E2 Ubiquitin Ligase Necessary for FANCD2 and FANCI Ubiquitination, Causes FA-T Subtype of Fanconi Anemia
af: Kimberly A. Rickman, et al.
Udgivet: (2015-07-01)

DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway
af: Sonali Bhattacharjee, et al.
Udgivet: (2017-10-01)

Lymphopenia With Clinical and Laboratory Features of Combined Immune Deficiency in an 11-Year-Old Female With FANCD2 Variants and Fanconi Anemia
af: Roman Deniskin, et al.
Udgivet: (2019-01-01)

The Fanconi Anemia C Protein Binds to and Regulates Stathmin-1 Phosphorylation.
af: Audrey Magron, et al.
Udgivet: (2015-01-01)

Microarray gene profiling analysis of glioblastoma cell line U87 reveals suppression of the FANCD2/Fanconi anemia pathway by the combination of Y15 and temozolomide
af: Zichuan Wang, et al.
Udgivet: (2019-06-01)

Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.
af: Cohn, M, et al.
Udgivet: (2008)

Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48
af: Georgia Velimezi, et al.
Udgivet: (2018-06-01)

Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia
af: Joanna Balcerek, et al.
Udgivet: (2018-09-01)

A role of Werner helicase interacting protein 1 in the Fanconi Anemia DNA repair pathway
af: Socha, A
Udgivet: (2017)

Fanconi Anemia: Exploration of DNA Repair Pathways from Genetic Diseases to Cancer and Prospects for Treatment
af: SHI Jinyu, et al.
Udgivet: (2024-01-01)

Studies of the DNA repair proteins FANCD2/FANCI and DNA polymerase eta
af: Liang, CC
Udgivet: (2012)

Studies of the Fanconi anemia pathway
af: Liang, C
Udgivet: (2016)

ATR-Mediated FANCI Phosphorylation Regulates Both Ubiquitination and Deubiquitination of FANCD2
af: Winnie Tan, et al.
Udgivet: (2020-02-01)

Cellular response to DNA interstrand crosslinks: The Fanconi Anemia pathway
af: Lopez-Martinez, D, et al.
Udgivet: (2016)

FANCD2 and CtIP Cooperate to Repair DNA Interstrand Crosslinks
af: Olga Murina, et al.
Udgivet: (2014-05-01)

Fanconi anemia pathway regulation by FANCI in prostate cancer
af: Heidi Kaljunen, et al.
Udgivet: (2023-10-01)

RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair
af: Lavina Sierra Tay, et al.
Udgivet: (2018-08-01)

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks prior to monoubiquitination of FANCD2
af: Liang, C, et al.
Udgivet: (2016)

The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
af: Chih-Chao Liang, et al.
Udgivet: (2016-07-01)

The Fanconi Anemia Pathway of Genomic Maintenance
af: Marieke Levitus, et al.
Udgivet: (2006-01-01)

WIP1 Contributes to the Adaptation of Fanconi Anemia Cells to DNA Damage as Determined by the Regulatory Network of the Fanconi Anemia and Checkpoint Recovery Pathways
af: Alfredo Rodríguez, et al.
Udgivet: (2019-05-01)