A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.

The insulin-like growth factor (IGF) pathway has been implicated in prostate development and carcinogenesis. We conducted a comprehensive analysis, utilizing a resequencing and tagging single-nucleotide polymorphism (SNP) approach, between common genetic variation in the IGF1, IGF binding protein (B...

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Bibliographic Details
Main Authors:	Schumacher, F, Cheng, I, Freedman, M, Mucci, L, Allen, N, Pollak, M, Hayes, R, Stram, DO, Canzian, F, Henderson, B, Hunter, D, Virtamo, J, Manjer, J, Gaziano, J, Kolonel, L, Tjønneland, A, Albanes, D, Calle, E, Giovannucci, E, Crawford, E, Haiman, C, Kraft, P, Willett, W, Thun, M, Le Marchand, L
Format:	Journal article
Language:	English
Published:	2010

A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians.

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