Signaling and polarized communication across the T cell immunological synapse
T cells express a somatically recombined antigen receptor (αβTCR) that is calibrated during development to respond to changes in peptides displayed by major histocompatibility complex proteins (pMHC) on the surface of antigen-presenting cells (APC). A key characteristic of pMHC for adaptive immunity...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Annual Reviews
2016
|