Signaling and polarized communication across the T cell immunological synapse

T cells express a somatically recombined antigen receptor (αβTCR) that is calibrated during development to respond to changes in peptides displayed by major histocompatibility complex proteins (pMHC) on the surface of antigen-presenting cells (APC). A key characteristic of pMHC for adaptive immunity...

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Bibliographic Details
Main Authors: Dustin, M, Choudhuri, K
Format: Journal article
Language:English
Published: Annual Reviews 2016