Signaling and polarized communication across the T cell immunological synapse
T cells express a somatically recombined antigen receptor (αβTCR) that is calibrated during development to respond to changes in peptides displayed by major histocompatibility complex proteins (pMHC) on the surface of antigen-presenting cells (APC). A key characteristic of pMHC for adaptive immunity...
Main Authors: | Dustin, M, Choudhuri, K |
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Format: | Journal article |
Language: | English |
Published: |
Annual Reviews
2016
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