Association of human antibodies to arabinomannan with enhanced mycobacterial opsonophagocytosis and intracellular growth reduction

Background: The relevance of antibodies (Abs) in the defense against Mycobacterium tuberculosis infection remains uncertain. We investigated the role of Abs to the mycobacterial capsular polysaccharide arabinomannan (AM) and its oligosaccharide fragments in humans. <br/>Methods: Sera from 29...

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Bibliographic Details
Main Authors: McShane, H, Tanner, R, Fletcher, H, Chen, T, Blanc, C, Eder, A, Prados-Rosales, R, Souza, A, Kim, R, Glatman-Freedman, A, Joe, M, Bai, Y, Lowary, T, Brennan, M, Casadevall, A, Achkar, J
Format: Journal article
Published: Oxford University Press 2016