Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS.

Clostridium difficile is a nosocomial bacterial pathogen causing antibiotic-associated diarrhea and fatal pseudomembranous colitis. Key virulence factors are toxin A and toxin B (TcdB), two highly related toxins that are members of the large clostridial toxin family. These large multifunctional prot...

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Bibliographic Details
Main Authors: Albesa-Jové, D, Bertrand, T, Carpenter, E, Swain, G, Lim, J, Zhang, J, Haire, L, Vasisht, N, Braun, V, Lange, A, von Eichel-Streiber, C, Svergun, D, Fairweather, N, Brown, K
Format: Journal article
Language:English
Published: 2010