Reduced somatostatin signalling leads to hypersecretion of glucagon in mice fed a high-fat diet
<p><strong>Objectives:</strong> Elevated plasma glucagon is an early symptom of diabetes, occurring in subjects with impaired glucose regulation. Here, we explored alpha-cell function in female mice fed a high-fat diet (HFD)—a widely used mouse model of prediabet...
Päätekijät: | Kellard, J, Rorsman, N, Hill, T, van der Bunt, M, Armour, S, Rorsman, P, Knudsen, J, Briant, L |
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Aineistotyyppi: | Journal article |
Kieli: | English |
Julkaistu: |
Elsevier
2020
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